HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Dibenzo[b,f]thiepin-3-carboxylic Acid 5-Oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Cyanodibenzo[b,f]thiepin 5-oxide | HCID 13151873 | — |
| Product | Dibenzo[b,f]thiepin-3-carboxylic Acid 5-Oxide | HCID 13151872 | — |
Reaction Steps
925 Mg. 3-cyanodibenzo[b,f]thiepin 5-oxide are refluxed for 31/2 hours in a mixture of 60 cc. 10% aqueous sodium hydroxide solution and 60 cc. denatured alcohol. The mixture is diluted with 1/2 liter of water and acidified with concentrated HCl. The acid precipitates and is filtered and dried. The yield of white dibenzo[b,f]thiepin-3-carboxylic acid 5-oxide is 965 mg. (97%), m.p. dec. 249° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04536507 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-9cf73a9c181b42159214521ad1695a87 |
| Source note | uspto-grants-1985_08 |