HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 8-Aminodibenzo[b,f]thiepin-3-carboxylic Acid Hydrochloride Salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 8-Amino-3-cyanodibenzo[b,f]thiepin | HCID 13151883 | — |
| Product | 8-Aminodibenzo[b,f]thiepin-3-carboxylic Acid Hydrochloride Salt | HCID 13151886 | — |
Reaction Steps
850 Mg. 8-amino-3-cyanodibenzo[b,f]thiepin is refluxed in a mixture of 20 cc. acetic acid and 20 cc. concentrated hydrochloric acid for 48 hours. The suspended solid is filtered, washed with some acetic acid, dried overnight under vacuum at 70° C. to yield 600 mg. pure compound, m.p. 308°-311° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04536507 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-0c386a8e0a534979a630886e6d209f2f |
| Source note | uspto-grants-1985_08 |