Acetic Acid → HCID 13151892, compound

HRID 485447Notes

Reaction equation

HRID 485447 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11](=[O:13])(=[O:12])[C:10]3[CH:14]=C(C#N)[CH:16]=[CH:17][C:9]=3[CH:8]=[CH:7][C:6]=2[CH:20]=1.S(=O)(=O)(O)O.[C:26]([OH:29])(=[O:28])[CH3:27]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11](=[O:13])(=[O:12])[C:10]3[CH:14]=[C:27]([C:26]([OH:29])=[O:28])[CH:16]=[CH:17][C:9]=3[CH:8]=[CH:7][C:6]=2[CH:20]=1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 1118Sulfuric AcidHCID 131518908-Chloro-3-cyanodibenzo[b,f]thiepin-5,5-dioxide

Product 1

HCID 13151892HCID 13151892, compound

Procedure

320 Mg. 8-chloro-3-cyanodibenzo[b,f]-thiepin-5,5-dioxide is refluxed for 24 hours in a mixture of 10 cc. acetic acid and 10 cc. 50% aqueous sulfuric acid. The mixture is cooled down and the crystalline product filtered, washed with water and dried at 70° C., 0.5 mm./Hg., to yield 289 mg. (82%) of pure acid, m.p. 276°-278° C.

Workup

  1. temperatureThe mixture is cooled down
  2. filtrationthe crystalline product filtered
  3. washwashed with water
  4. customdried at 70° C.
  5. custom, to yield 289 mg

Sources & evidence

ORD record
ord-c290291603cb49b59bb835004f28ca76
Source dataset
uspto-grants-1985_08
Patent number
US04536507

Reaction notes

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