反应详情

1.7 g (10 mmol) of 6-chloroguanine and 1.2 g (10 mmol) of selenourea were put in 30 ml of absolute ethanol and boiled under reflux for 2 hours. After completion of the reaction, the resulting precipitate was separated by filtration, washed with water and dissolved in 200 ml of 2wt % aqueous sodium carbonate solution by heating. The resulting solution was acidified with acetic acid to form crystals. The crystals were separated by filtration and dried to obtain 1.5 g (7 mmol) of 6-selenoguanine.

1. temperatureunder reflux for 2 hours
2. customAfter completion of the reaction
3. customthe resulting precipitate was separated by filtration
4. washwashed with water
5. dissolutiondissolved in 200 ml of 2wt % aqueous sodium carbonate solution
6. temperatureby heating
7. customto form crystals
8. customThe crystals were separated by filtration
9. customdried