Carbon Dioxide → HCID 12853038, compound

Participants

Reaction Steps

The ethyl α,α-diacetyl-β-(2-fluorophenyl)glutarate was heated under vacuum at 160°-180°/10-15 mm for 1 hr, eliminating carbon dioxide and ethanol and producing 5-(2-fluorophenyl)-3-methyl-4-carbethoxy-2-cyclohexen-1-one. The crude product was distilled under reduced pressure to give 5-(2-fluorophenyl)-3-methyl-4-carbethoxy-2-cyclohexen-1-one (57.3 g); bp, 155°-162°/1.2 mm.

Provenance & Evidence