Acetone → HCID 13316488, compound

Participants

Reaction Steps

L-phenylalaninol (31.3 g) was dissolved in a mixture of acetone (23 ml) and ethanol (120 ml). The solution was shaken in an atmosphere of hydrogen in the presence of platinum oxide (0.1 g) until the calculated amount of hydrogen was absorbed. The catalyst was filtered off and the filtrate was concentrated to dryness under reduced pressure to give N-isopropyl-L-phenylalaninol (40 g), mp 65°-66° C., [α]D -5.4°.

Provenance & Evidence