Hydrazine hydrate (1:1) → HCID 13470300, compound

Participants

Reaction Steps

Using a procedure similar to that described in Example 1, 0.5 mole of methyl 3-methylaminocrotonate and 0.5 mole of 3-[2-(2chlorophenoxy)-ethoxy]-benzoyl chloride are converted to methyl 3-methylamino-2-[3-(2-(2-chlorophenoxy)-ethoxy)-benzoyl]-crotonate of melting point 131°-133° C., the yield being 58%. When reacted with hydrazine hydrate by a procedure similar to that described in Example 1, this ester gives 5-methyl-4-methoxycarbonyl-3-[3-(2-(2-chlorophenoxy)-ethoxy)-phenyl]-pyrazole of melting point 127°-129° C., the yield being 59%.

Provenance & Evidence