HCID 13729462, compound → HCID 20268361, compound

HRID 485612Notes

Reaction equation

HRID 485612 reaction equation
[F:1][C:2]([F:22])([O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[S:14]([NH:17][C:18](NC)=[O:19])(=[O:16])=[O:15])[C:3]([F:6])([F:5])[F:4]>ClC1C=CC=CC=1>[F:22][C:2]([F:1])([O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[S:14]([N:17]=[C:18]=[O:19])(=[O:15])=[O:16])[C:3]([F:6])([F:5])[F:4]

Participants

3

Reactant 1

HCID 13729462HCID 13729462, compound

Product 1

HCID 20268361HCID 20268361, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

74.6 g of N-(2-pentafluoroethoxyphenylsulfonyl)-N'-methylurea are suspended in 1300 ml of chlorobenzene and made absolute by distilling off about 100 ml of solvent as an azeotrope. Then 48 g of phosgene are introduced at 120°-130° C. over 3 hours. The chlorobenzene is then completely distilled off, affording 65 g of 2-pentafluoroethoxyphenylsulfonyl isocyanate in the form of an almost colourless oil.

Workup

  1. distillationby distilling off about 100 ml of solvent as an azeotrope
  2. additionThen 48 g of phosgene are introduced at 120°-130° C. over 3 hours
  3. distillationThe chlorobenzene is then completely distilled off

Sources & evidence

ORD record
ord-dbc427dfa5f548249bbc4f1de93d9fe9
Source dataset
uspto-grants-1985_08
Patent number
US04537619

Reaction notes

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