Dimethylamine → 2-[2-(Dimethylamino)ethyl]-2,3-dihydro-4,10-dimethyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione hydrochloride

HRID 4857Notes

Reaction equation

HRID 4857 reaction equation
[Cl:1][CH2:2][CH2:3][CH:4]1[CH2:19][N:18]([CH3:20])[C:17](=[S:21])[C:7]2[CH:8]=[CH:9][C:10]3[CH:11]=[CH:12][C:13]([CH3:16])=[N:14][C:15]=3[C:6]=2[O:5]1.[CH3:22][NH:23][CH3:24]>>[ClH:1].[CH3:22][N:23]([CH3:24])[CH2:2][CH2:3][CH:4]1[CH2:19][N:18]([CH3:20])[C:17](=[S:21])[C:7]2[CH:8]=[CH:9][C:10]3[CH:11]=[CH:12][C:13]([CH3:16])=[N:14][C:15]=3[C:6]=2[O:5]1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 212715292-(2-chloroethyl)-2,3-dihydro-4,10-dimethyl-1,4-oxazepino[6,7-h)quinoline-5(4H)-thione

Product 1

HCID 212714572-[2-(Dimethylamino)ethyl]-2,3-dihydro-4,10-dimethyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione hydrochloride

Procedure

Following the procedure of Example 31, 2-(2-chloroethyl)-2,3-dihydro-4,10-dimethyl-1,4-oxazepino[6,7-h)quinoline-5(4H)-thione is reacted with dimethylamine to give the title compound.

Sources & evidence

ORD record
ord-b5c30907b10f4115832fbf4e0039c599
Source dataset
uspto-grants-1988_02
Patent number
US04727152

Reaction notes

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