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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485750Generated: October 30, 2026

2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-methyl- → 1-(2-Methylamino-5-chlorobenzoyl)-1H-indazol-3-ol

https://huagongshe.com/reaction/485750

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-methyl-HCID 26724—
ReactantIndazolinoneHCID 81829—
Product1-(2-Methylamino-5-chlorobenzoyl)-1H-indazol-3-olHCID 17848214833.5%

Reaction Steps

1H-Indazol-3-ol was reacted with N-methyl-5-chloroisatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 33.5% yield; m.p. 210°-213° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04537966
Source datasetuspto-grants-1985_08
ORD IDord-8fe2ed2019f7483aa6fa2ac88f9e5b10
Source noteuspto-grants-1985_08