Indazolinone → HCID 178482141, compound

HRID 485751Notes

Reaction equation

HRID 485751 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1.[CH3:11][N:12]1C(=O)O[C:15](=[O:16])[C:14]2=[CH:20][C:21]([CH3:24])=[CH:22][CH:23]=[C:13]12>>[CH3:11][NH:12][C:13]1[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][C:14]=1[C:15]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1)=[O:16]

Participants

3

Reactant 2

HCID 81829IndazolinoneHCID 123694572H-3,1-Benzoxazine-2,4(1H)-dione, 1,6-dimethyl-

Product 1

HCID 178482141HCID 178482141, compoundYield 40.5%

Procedure

1H-Indazol-3-ol was reacted with N-methyl-5-methylisatoic anhydride according to the general procedue A above and afforded the desired amine as yellow solid in 40.5% yield; m.p. 173°-175° C.

Sources & evidence

ORD record
ord-686fa718ddc541dc9102e1a43a240d79
Source dataset
uspto-grants-1985_08
Patent number
US04537966

Reaction notes

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