Indazolinone → HCID 178482211, compound

HRID 485752Notes

Reaction equation

HRID 485752 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1.[CH3:11][N:12]1C(=O)O[C:15](=[O:16])[C:14]2=[CH:20][C:21]([O:24][CH3:25])=[CH:22][CH:23]=[C:13]12>>[CH3:11][NH:12][C:13]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:14]=1[C:15]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1)=[O:16]

Participants

3

Reactant 2

HCID 81829IndazolinoneHCID 12225972HCID 12225972, compound

Product 1

HCID 178482211HCID 178482211, compoundYield 40.6%

Procedure

1H-Indazol-3-ol was reacted with N-methyl-5-methoxy isatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 40.6% yield; m.p. 161°-163° C.

Sources & evidence

ORD record
ord-a61f652ff9744cbc8899c6a5e8337c2f
Source dataset
uspto-grants-1985_08
Patent number
US04537966

Reaction notes

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