Benzoyl chloride, 3-nitro- → HCID 178519604, compound

Participants

Reaction Conditions

Reaction Steps

To 16.0 (0.118 mol) of 1H-indazol-3-ol dissolved in 120 ml of dry pyridine was added 21.8 g (0.118 mol) of m-nitrobenzoyl chloride. The heterogeneous yellow mixture was heated at 95° C. for 21/2 hrs. then let cool to room temperature and poured onto 1 liter of ice/H2O. The light yellow precipitate was collected, washed well with H2O and air-dried. Recrystallization from aqueous EtOH afforded 12.7 g (27.9%) of 1-(m-nitrobenzoyl)-1H-indazol-3-ol as a colorless solid, mp 232°-234° C.

Provenance & Evidence