N-Methylisatoic anhydride → HCID 178482123, compound

HRID 485756Notes

Reaction equation

HRID 485756 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([OH:11])=[N:7][NH:8]2)=[CH:4][CH:3]=1.[CH3:12][N:13]1C(=O)O[C:16](=[O:17])[C:15]2=[CH:21][CH:22]=[CH:23][CH:24]=[C:14]12>>[CH3:12][NH:13][C:14]1[CH:24]=[CH:23][CH:22]=[CH:21][C:15]=1[C:16]([N:8]1[C:9]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:10]=2)[C:6]([OH:11])=[N:7]1)=[O:17]

Participants

3

Reactant 2

HCID 25160N-Methylisatoic anhydrideHCID 178518960HCID 178518960, compound

Product 1

HCID 178482123HCID 178482123, compoundYield 59%

Procedure

6-Chloro-1H-indazol-3-ol was reacted with N-methylisatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 59.0% yield; m.p. 203°-205° C.

Sources & evidence

ORD record
ord-c6d6e48dfea24075ae0cfe530a199efe
Source dataset
uspto-grants-1985_08
Patent number
US04537966

Reaction notes

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