N-Methylisatoic anhydride → HCID 178482126, compound

HRID 485758Notes

Reaction equation

HRID 485758 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][N:8]=[C:7]2[OH:13])([O-:3])=[O:2].[CH3:14][N:15]1C(=O)O[C:18](=[O:19])[C:17]2=[CH:23][CH:24]=[CH:25][CH:26]=[C:16]12>>[CH3:14][NH:15][C:16]1[CH:26]=[CH:25][CH:24]=[CH:23][C:17]=1[C:18]([N:9]1[C:10]2[C:6](=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:12][CH:11]=2)[C:7]([OH:13])=[N:8]1)=[O:19]

Participants

3

Reactant 2

HCID 25160N-Methylisatoic anhydrideHCID 178526496HCID 178526496, compound

Product 1

HCID 178482126HCID 178482126, compoundYield 47%

Procedure

5-Nitro-1H-indazol-3-ol was reacted with N-methylisatoic anhydride according to the general procedure A above and afforded the desired amine as an orange solid in 47.0% yield; m.p. >270° C.

Sources & evidence

ORD record
ord-9f5b4211857541bb9f52ac0eefa6199b
Source dataset
uspto-grants-1985_08
Patent number
US04537966

Reaction notes

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