N-Methylisatoic anhydride → HCID 178482127, compound

HRID 485760Notes

Reaction equation

HRID 485760 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[NH:8][N:7]=[C:6]2[OH:12].[CH3:13][N:14]1C(=O)O[C:17](=[O:18])[C:16]2=[CH:22][CH:23]=[CH:24][CH:25]=[C:15]12>>[CH3:13][NH:14][C:15]1[CH:25]=[CH:24][CH:23]=[CH:22][C:16]=1[C:17]([N:8]1[C:9]2[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:11][CH:10]=2)[C:6]([OH:12])=[N:7]1)=[O:18]

Participants

3

Reactant 2

HCID 25160N-Methylisatoic anhydrideHCID 178488171HCID 178488171, compound

Product 1

HCID 178482127HCID 178482127, compound

Procedure

5-Methoxy-1H-indazol-3-ol was reacted with N-methylisatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 67.0% yeild; m.p. 175°-177° C.

Sources & evidence

ORD record
ord-9387de68182944bdbca51a6c28ebd0b5
Source dataset
uspto-grants-1985_08
Patent number
US04537966

Reaction notes

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