Pyridinium chloride → HCID 13290005, compound

Participants

Reaction Steps

A mixture of 5.6 g of 6,7-dichloro-5-methoxy-3-methylbenzo[b]-thiophene and 50 g of pyridine hydrochloride is stirred at 190°-195° for 2 hours. The cooled reaction mixture is diluted with water and extracted with three 300 ml-portions of ether. The combined ether extracts are washed, dried and concentrated to give a tan-colored solid, mp 137°-139°. Recrystallization from hexane gives 3.8 g of 6,7-dichloro-5-hydroxy-3-methylbenzo[b]thiophene as silky needles.

Provenance & Evidence