HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → Sec.Butyl Bis(beta-Carboxyethyl)Phosphine Oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Methyl Acrylate | HCID 7294 | — |
| Reactant | Butanenitrile, 2,2'-azobis[3-methyl- | HCID 11240960 | — |
| Reactant | (Butan-2-yl)phosphane | HCID 13810228 | — |
| Reactant | Sec. butylbis(carbomethoxyethyl)phosphine | HCID 131714320 | — |
| Product | Sec.Butyl Bis(beta-Carboxyethyl)Phosphine Oxide | HCID 22902895 | — |
Reaction Steps
Sec. butylphosphine, 592 parts (85% purity) is reacted with 860 parts of methyl acrylate containing 4.9 parts of azobis(isovaleronitrile) at 67°-100° C. for 3.5 hours. The reaction product, sec. butylbis(carbomethoxyethyl)phosphine is reacted with 10% molar excess hydrogen peroxide (25% solution) for two hours at 60° C. to give the corresponding phosphine oxide. The latter is hydrolyzed with dilute sulfuric acid to give after recrystallization from water, sec. butyl bis(β-carboxyethyl)phosphine oxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04537993 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-79fe421a302d4e3aa58cc969247964e1 |
| Source note | uspto-grants-1985_08 |