Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48603Generated: October 25, 2026

1-Benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline → 2-(1-Benzyl-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-N-(2,5-difluoro-benzyl)-acetamide

https://huagongshe.com/reaction/48603

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolineHCID 30024—
ReactantBromoacetyl bromideHCID 61147—
Reactant2,5-DifluorobenzylamineHCID 123589—
Product2-(1-Benzyl-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-N-(2,5-difluoro-benzyl)-acetamideHCID 22742620—

Reaction Steps

prepared by reaction of 1-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2,5-difluorobenzylamine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703392B2
Source datasetuspto-grants-2004_03
ORD IDord-6adf086a82bb4f2b97f987b9a694ada8
Source noteuspto-grants-2004_03