Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 178418361, 화합물 → HCID 178520964, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 반응물 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol | HCID 178521066 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 생성물 | HCID 178520964 | HCID 178520964 | — |
반응 단계
In Step 4, inosine derivative (IV') is subjected to reduction with hydrogen (H2) in an organic solvent over a palladium catalyst. This reduction proceeds with minimum substrate decomposition. This is followed by hydrolysis or ester exchange reaction, giving 2',3'-dideoxyinosine derivative (A').
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05290927 |
| 출처 데이터셋 | uspto-grants-1994_03 |
| ORD ID | ord-91215ee351214a4795c52a806e965441 |
| 출처 메모 | uspto-grants-1994_03 |