Dichloromethane → HCID 178459584, compound

Participants

Reaction Steps

The reaction mixture from step 1 was cooled under nitrogen and then diluted with 200 g. of methylene chloride. Then, 289 g. of acetic anhydride, along with a catalyst of 0.5 g. of 4-dimethylaminopyridine, were added to the reaction mixture. The reaction mixture was stirred for 1 hour at which time NMR analysis of a vacuum stripped aliquot indicated complete conversion to the desired thioacetate. The product was distilled at 132°-134° C. at 20 mm Hg to yield 355 g. of product (80%).

Provenance & Evidence