Water → HCID 19094964, compound

Participants

Reaction Steps

A solution of 10.62 g of 4-chlorocyclohexanecarboxalde-hyde in 150 ml of toluene is treated with 11.5 ml of 1,3-propanediol and 1 g of Amberlyst® 15 and heated to boiling for 2 hours on a water separator while stirring. The reaction mixture is treated with 2 ml of triethylamine and, after cooling, is filtered. The filtrate is washed three times with 30 ml of water, dried over sodium sulphate and concentrated. There is obtained 2-(4-chlorocyclohexyl)-1,3-dioxane.

Provenance & Evidence