HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-Amino-5-[3-(pentylthio)propylthio]-1,2,4-triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Chloropropyl pentyl sulfide | HCID 19023126 | — |
| Reactant | 3-Amino-5-{2-[2-(hexylthio)ethylthio]ethylthio}-1,2,4-triazole | HCID 178445574 | — |
| Reactant | 5-amino-1H-1,2,4-triazole-3-thiol | HCID 178509296 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Amino-5-[3-(pentylthio)propylthio]-1,2,4-triazole | HCID 178447705 | — |
Reaction Steps
Compound 9 was prepared from a mixture of 3-chloropropyl pentyl sulfide, 3-amino-5-mercapto-1,2,4-triazole and pyridine in acetonitrile, as described previously for Compound 12. The reaction mixture was poured into water and extracted with CH2Cl2. The extracts were washed with water and brine, dried over MgSO4, and concentrated under vacuum to provide Compound 9 in 71% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05292627 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-e6c26a24494a483faac30057276f6133 |
| Source note | uspto-grants-1994_03 |