HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 486424Generated: October 30, 2026
Lithium Chloride → Cyclopentanone, 2-(2-methyl-2-propenyl)-
https://huagongshe.com/reaction/486424
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lithium Chloride | HCID 433294 | — |
| Reactant | HCID 19391891 | HCID 19391891 | — |
| Solvent | Hexamethylphosphoramide | HCID 12679 | — |
| Product | Cyclopentanone, 2-(2-methyl-2-propenyl)- | HCID 12222022 | — |
Reaction Steps
A mixture of methyl-1-(2-methyl-2-propenyl)-2-oxo-1-cyclopentanecarboxylate (78.4 g), HMPA (hexamethylphosphoramide, 250 ml) and LiCl (34 g) is heated to 73° C. for 36 hrs. Extraction (3 times, ether/water) of the reaction product provides a brown oil which, upon fractional distillation (63° C.-75° C./5.32×102Pa), yields 2-(2-methyl-2-propenyl)-1-cyclopentanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05292719 |
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| Source dataset | uspto-grants-1994_03 |
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| ORD ID | ord-9c32e307e20b402b87209b0f4dc12dd7 |
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| Source note | uspto-grants-1994_03 |
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