Oxalic Acid → HCID 54188933, compound

HRID 486544Notes

Reaction equation

C(O)(=O)C(O)=O.C[O:8][CH:9](OC)[CH2:10][CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][C:15]([Cl:21])=[CH:16][CH:17]=2)[C:12]1=[O:22]>>[Cl:21][C:15]1[CH:14]=[C:13]2[C:18]([CH2:19][CH2:20][CH:11]([CH2:10][CH:9]=[O:8])[C:12]2=[O:22])=[CH:17][CH:16]=1

Participants

Reactant 2

HCID 971Oxalic Acid

HCID 19095306HCID 19095306, compound

Product 1

HCID 54188933HCID 54188933, compoundYield 95.5%

Procedure

For the acetal cleavage, 15 ml of a 10% aqueous oxalic acid solution were applied to 100 g of silica gel and 4.8 g of 7-chloro-1,2,3,4-tetrahydro-1-oxo-2-naphthaleneacetaldehyde dimethyl acetal were chromatographed on this mixture with methylene chloride as the eluent. There were obtained 3.8 g (95%) of 7-chloro-1,2,3,4-tetrahydro-1-oxo-2-naphthalene-acetaldehyde.

Workup

customwere chromatographed on this mixture with methylene chloride as the eluent

Sources & evidence

ORD record: ord-18a9f8596d454725ab75f0ec538d5a95
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05292732

Reaction notes

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