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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48661Generated: October 26, 2026

1,3,4-Thiadiazol-2-amine → 2-[1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[1,3,4]thiadiazol-2-yl-acetamide

https://huagongshe.com/reaction/48661

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3,4-Thiadiazol-2-amineHCID 19909—
ReactantBromoacetyl bromideHCID 61147—
Reactant1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinolineHCID 22742643—
Product2-[1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[1,3,4]thiadiazol-2-yl-acetamideHCID 22742591—

Reaction Steps

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-amino-1,3,4-thiadiazole

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703392B2
Source datasetuspto-grants-2004_03
ORD IDord-784fe9b2029a4553a0dbbd14cae472c2
Source noteuspto-grants-2004_03