4-tert-Butylbenzenesulfonamide → HCID 19432676, compound

HRID 486645Notes

Reaction equation

HRID 486645 reaction equation
Cl[C:2]1[C:7]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH3:16])=[C:6](Cl)[N:5]=[C:4]([CH2:18][CH2:19][CH3:20])[N:3]=1.[C:21]([C:25]1[CH:30]=[CH:29][C:28]([S:31]([NH2:34])(=[O:33])=[O:32])=[CH:27][CH:26]=1)([CH3:24])([CH3:23])[CH3:22]>>[C:21]([C:25]1[CH:30]=[CH:29][C:28]([S:31]([NH:34][C:2]2[C:7]([O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[O:15][CH3:16])=[C:6]([O:8][CH2:9][CH2:10][OH:15])[N:5]=[C:4]([CH2:18][CH2:19][CH3:20])[N:3]=2)(=[O:32])=[O:33])=[CH:27][CH:26]=1)([CH3:24])([CH3:22])[CH3:23]

Participants

3

Reactant 2

HCID 2228724-tert-ButylbenzenesulfonamideHCID 19095741HCID 19095741, compound

Product 1

HCID 19432676HCID 19432676, compound

Procedure

By reacting 4,6-dichloro-5-(o-methoxyphenoxy)-2-propylpyrimidine with p-tert-butylphenylsulfonamide and thereafter with ethylene glycol Na, there was obtained p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-propyl-4-pyrimidinyl]-benzenesulfonamide.

Sources & evidence

ORD record
ord-16f54a7ac7be440f97fc441f91c8d8fa
Source dataset
uspto-grants-1994_03
Patent number
US05292740

Reaction notes

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