Water → HCID 54017596, compound

Participants

Reaction Steps

To a stirred solution of (2R,4R)-2-acetylthiomethyl-4-carboxytetrahydrothiophene (compound No. 13-2, 0.18 g) in dimethylformamide (4 ml), benzyl bromide dissolved in dimethylformamide (4 ml) and diisopropylamine (214 μl) were added and the mixture was stirred over night. Water was added to the mixture and extracted with diethylether. The organic layer was washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate and concentrated in vacuo. The oily residue was purified by a silica gel column chromatography to give 0.18 g (71%) of the titled compound (compound No. 14-1).

Provenance & Evidence