Bromoacetyl bromide → 2-[1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[(1S,2R)-2-hydroxy-indan-1-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	Bromoacetyl bromide	HCID 61147	—
Reactant	(1S,2R)-(-)-1-Amino-2-indanol	HCID 9866743	—
Reactant	1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline	HCID 22742709	—
Product	2-[1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[(1S,2R)-2-hydroxy-indan-1-yl]-acetamide	HCID 69895773	—

Reaction Steps

prepared by reaction of 1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with (1S,2R)-1-amino-2-indanol

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06703392B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-e5e826901ea44b8fbc7f322df2ad980b
Source note	uspto-grants-2004_03