Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 3-Bromo-N-phenylaniline | HCID 14958606 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 18965182 | HCID 18965182 | — |
Reaction Steps
A solution of 15.0 g (60.4 mmole) of 3-bromodiphenylamine [i.e., N-(3-bromophenyl)aniline] [S. Kurzepa and J. Cieslak, Roczniki Chem., 34, 111 (1960)] in 30 ml of toluene and 50 ml (116 mmole) of 1.93M phosgene in toluene were combined and heated at 90° C. under nitrogen for 2 hours with stirring. The red orange colored solution was cooled, flushed with nitrogen for 2 hours to remove excess Phosgene and concentrated in vacuo to 18.0 g (58.0 mmole, 96%) of red orange oil which was homogeneous by TLC (4:1 hexane-ethyl acetate, Rf =0.80).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05292726 |
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| Source dataset | uspto-grants-1994_03 |
|---|
| ORD ID | ord-607c8589fd264ac498f6637306d4054f |
|---|
| Source note | uspto-grants-1994_03 |
|---|
