Hydrochloric Acid → HCID 19094238, compound

Participants

Reaction Steps

2-Bromo-5-chloro-3-nitrobenzoic acid (2.30 g, 10 mmol) was refluxed with 2-chlorobenzyl amine (20 mmol, 2.82 g) overnight. The reaction mixture was then poured into 10% aqueous hydrochloric acid solution and the resulting solid was collected. Crystallization from aqueous methanol gave 1.81 g (53%) of 5-chloro[(2-chlorophenyl)methyl]amino-3-nitrobenzoic acid; mp 159.5°-161° C.

Provenance & Evidence