HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 10254661, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cgs 25462 | HCID 132812 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10254661 | HCID 10254661 | — |
Reaction Steps
(S)-N-[2-(Diphenylphosphonomethylamino)-3-(4-biphenylyl)-propionyl]-3-aminopropionic acid (100 mg, 0.18 mmol) is dissolved in acetonitrile (10 mL) containing 5% 1N HCl. The mixture is refluxed for 3 hours. The precipitate is filtered and triturated with aqueous methanol to yield (S)-N-[2-(monophenylphosphonomethylamino)-3-(4-biphenylyl)-propionyl]-3-aminopropionic acid as a monohydrate, m.p. 222°-223°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05294632 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-e422c04908534a1e8bef18d036e49a24 |
| Source note | uspto-grants-1994_03 |