Acetic Anhydride → 6-(4-Acetoxypiperidino)-3,4-dihydrocarbostyril

Participants

Reaction Steps

To a solution of 200 mg of 6-(4-hydroxypiperidino)-3,4-dihydrocarbostyril in 2 ml of pyridine were added 92 mg of acetic anhydride and 10 mg of 4-dimethylaminopyridine. After stirring at room temperature for 40 hr, the reaction mixture was concentrated under a reduced pressure, and the resulting residue was purified by a silica gel column chromatography to give 226 mg of 6-(4-acetoxypiperidino)-3,4-dihydrocarbostyril.

Provenance & Evidence