2-Amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid ethyl ester → 2-Amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid

HRID 487450Notes

Reaction equation

HRID 487450 reaction equation
C([O:3][C:4](=[O:18])[CH:5]([NH2:17])[CH:6]=[C:7]([CH2:12][P:13]([OH:16])([OH:15])=[O:14])[CH2:8][CH2:9][O:10][CH3:11])C>O>[NH2:17][CH:5]([CH:6]=[C:7]([CH2:12][P:13]([OH:16])([OH:15])=[O:14])[CH2:8][CH2:9][O:10][CH3:11])[C:4]([OH:18])=[O:3]

Participants

3

Reactant 1

HCID 537927812-Amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid ethyl ester

Product 1

HCID 542642022-Amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.98 g (3.5 mmol) of 2-amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid ethyl ester is heated under reflux in 7 ml of water for 17 hours. The reaction mixture is concentrated by evaporation and crystallised from a mixture of water and ethanol. 2-amino-6-methoxy-4-phosphonomethyl-hex-3-enoic acid having a melting point of 214° C. (decomp.) is obtained.

Workup

  1. concentrationThe reaction mixture is concentrated by evaporation
  2. customcrystallised from a mixture of water and ethanol

Sources & evidence

ORD record
ord-d5966a20f1524c53a8f9984e3fdaf5c9
Source dataset
uspto-grants-1994_03
Patent number
US05294734

Reaction notes

Loading…