Bromoacetyl bromide → 2-[1-(3,4-Dimethoxy-benzyl)-6,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[(1R,2S)-2-hydroxy-indan-1-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	Bromoacetyl bromide	HCID 61147	—
Reactant	(1R,2S)-(+)-cis-1-Amino-2-indanol	HCID 2725045	—
Reactant	1-(3,4-Dimethoxy-benzyl)-6,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline	HCID 22643329	—
Product	2-[1-(3,4-Dimethoxy-benzyl)-6,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-[(1R,2S)-2-hydroxy-indan-1-yl]-acetamide	HCID 69897887	—

Reaction Steps

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with (1R,2S)-1-amino-2-indanol

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06703392B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-42a3be181e4144f08932d426ddcbda90
Source note	uspto-grants-2004_03