Bromine → HCID 19092144, compound

HRID 487551Notes

Reaction equation

HRID 487551 reaction equation
[C:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][C:9](=[O:12])[NH:10][O:11][C:6]=2[CH:5]=1)(=[O:3])[CH3:2].[Br:15]Br>C(Cl)Cl>[Br:15][CH2:2][C:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][C:9](=[O:12])[NH:10][O:11][C:6]=2[CH:5]=1)=[O:3]

Participants

4

Reactant 2

HCID 24408BromineHCID 19092089HCID 19092089, compound

Product 1

HCID 19092144HCID 19092144, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.01 mol of 7-acetylbenzoxazinone, described in Application EP 223,674, is dissolved in 100 cm3 of methylene chloride. 0.011 mol of bromine is added dropwise and with stirring via a dropping funnel, and stirring is maintained for 13 hours. The mixture is filtered and evaporated to dryness and the residue is recrystallized.

Workup

  1. stirringstirring
  2. temperatureis maintained for 13 hours
  3. filtrationThe mixture is filtered
  4. customevaporated to dryness
  5. customthe residue is recrystallized

Sources & evidence

ORD record
ord-530e1f3ad0014488a010819520cae80f
Source dataset
uspto-grants-1994_03
Patent number
US05296477

Reaction notes

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