1,2,3,4-Tetrahydroisoquinoline → HCID 19092274, compound

HRID 487573Notes

Reaction equation

HRID 487573 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][C:13](=O)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][NH:18]1>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][CH:13]([N:18]3[CH2:19][CH2:20][C:21]4[C:26](=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH2:17]3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 38425621-(4-Nitrophenyl)piperidin-4-one

Product 1

HCID 19092274HCID 19092274, compound

Procedure

3.0 g of 1-(4-nitrophenyl)-4-piperidone and 1.8 g of 1,2,3,4-tetrahydroisoquinoline were reacted as in Example 1.

Sources & evidence

ORD record
ord-910872152c3a460eaa220cac5a5d127f
Source dataset
uspto-grants-1994_03
Patent number
US05296485

Reaction notes

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