4-Tert-butyl-2-[5-{2-(2-ethoxycarbonylphenyl)ethenyl}benzofuran-2-yl]thiazole → 4-Tert-butyl-2-[5-{2-(2-ethoxycarbonylphenyl)ethyl}benzofuran-2-yl]thiazole

Participants

Reaction Steps

To a solution of 4-tert-butyl-2-[5-{2-(2-ethoxycarbonylphenyl)ethenyl}benzofuran-2-yl]thiazole (250 mg) in methanol (20.0 ml), 10% palladium on carbon (140 mg) was added. The mixture was hydrogenated for 3 hours (3.0-2.3 atm). The catalyst was removed by filtration and washed with methanol. The filtrate was evaporated under reduced pressure to give 4-tert-butyl-2-[5-{2-(2-ethoxycarbonylphenyl)ethyl}benzofuran-2-yl]thiazole (270 mg).

Provenance & Evidence