HCID 86747686, compound → HCID 57175590, compound

Participants

Reaction Steps

Silica (18 g, Merck Kieselgel 60) was added to a solution of the product of step (a) (300 mg) in dichloromethane (100 ml). Volatiles were then removed in vacuo at room temperature and the resulting freely flowing powder was stored at 8° C. for 16 hours. The support was then washed with acetone containing triethylamine and the solvent was evaporated in vacuo to an oil. Chromatography on silica eluting with hexane in an acetone gradient then gave the title compound as a foam (79 mg).

Provenance & Evidence