Ethyl Acetate → HCID 57215774, compound

Participants

Reaction Steps

A portion of the product from step (a) (13 mg) was dissolved in acetonitrile (4 ml) and to this was added 40% aqueous hydrofluoric acid (0.1 ml). After stirring for 2 hours at room temperature the reaction mixture was poured into ethyl acetate and the separated organic extract was then washed with water, saturated aqueous sodium hydrogen carbonate solution and brine before being dried (MgSO4), filtered and evaporated to an oil in vacuo. Column chromatography on silica eluting with hexane/acetone [2:1] then gave the title compound (8 mg) as a foam.

Provenance & Evidence