HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Bromomethyl)-1-methylquinolin-2(1H)-one → Ethyl 2-methyl-2-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]butyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Bromomethyl)-1-methylquinolin-2(1H)-one | HCID 15199065 | — |
| Reactant | Ethyl 2-(3-hydroxyphenyl)-2-methylbutyrate | HCID 19091445 | — |
| Product | Ethyl 2-methyl-2-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]butyrate | HCID 67826098 | 44% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 6-bromomethyl-1-methyl-1,2-dihydroquinolin-2-one was reacted with ethyl 2-(3-hydroxyphenyl)-2-methylbutyrate to give ethyl 2-methyl-2-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]butyrate in 44% yield as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298511 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-bd818f65a29949fe8b7456db855de292 |
| Source note | uspto-grants-1994_03 |