Diethyl Ether → HCID 19091378, compound

Participants

Reaction Steps

A mixture of 25.8 g (0.15 mol) of N-[2-(methoxyimino)ethyl]oxazolidinone 22 and 9 g (0.15 mol) of ethylenediamine in 50 mL of absolute ethanol was refluxed for 30 min. After cooling to room temperature, the mixture was treated with ether until crystals separated and then was refrigerated for 3 days. The colorless crystals were filtered and dried to give 19.9 g (73%) of 23: mp 118°-123° C.; 1H NMR (CDCl3) δ 2.54 (t, 2, --CH2 --C(=N) 3.57 (s, 4, =NCH2CH2 --NH), 3.62 (m, 4, --CH2NCH2), 4.32 (m, 2, --OCH2), 4.57 (b, NH). Anal. C8H13N3O2): C, 52.25; H, 7.15; N, 22.80.

Provenance & Evidence