Ethyl bromoacetate → HCID 69894100, compound

HRID 48793Notes

Reaction equation

HRID 48793 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:31]=[CH:32][C:33]=1[O:34][CH3:35])[CH2:6][CH:7]1[C:16]2[C:11](=[CH:12][C:13]([OH:19])=[C:14]([O:17][CH3:18])[CH:15]=2)[CH2:10][CH2:9][N:8]1[CH2:20][C:21]([NH:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:22].Br[CH2:37][C:38]([O:40][CH2:41][CH3:42])=[O:39]>>[CH2:41]([O:40][C:38](=[O:39])[CH2:37][O:19][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][C:14]=1[O:17][CH3:18])[CH:7]([CH2:6][C:5]1[CH:31]=[CH:32][C:33]([O:34][CH3:35])=[C:3]([O:2][CH3:1])[CH:4]=1)[N:8]([CH2:20][C:21](=[O:22])[NH:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH2:9][CH2:10]2)[CH3:42]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 227426232-[1-(3,4-dimethoxy-benzyl)-6-hydroxy-7-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide

Product 1

HCID 69894100HCID 69894100, compound

Procedure

prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-6-hydroxy-7-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide with ethyl bromoacetate

Sources & evidence

ORD record
ord-7c60d6c4cafd421fb397e6d09970e0fe
Source dataset
uspto-grants-2004_03
Patent number
US06703392B2

Reaction notes

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