Ethanol, 2-amino-, 1-nitrate, nitrate (1:1) → N-(2-Nitrooxyethyl)-2-oxo-5-(3-pyridyl)thiazolidine-4-carboxamide

HRID 487953Notes

Reaction equation

HRID 487953 reaction equation
[N+]([O-])(O)=O.[N+:5]([O:8][CH2:9][CH2:10][NH2:11])([O-:7])=[O:6].[O:12]=[C:13]1[NH:17][CH:16]([C:18](O)=[O:19])[CH:15]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)[S:14]1>>[N+:5]([O:8][CH2:9][CH2:10][NH:11][C:18]([CH:16]1[CH:15]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)[S:14][C:13](=[O:12])[NH:17]1)=[O:19])([O-:7])=[O:6]

Participants

3

Reactant 2

HCID 78397Ethanol, 2-amino-, 1-nitrate, nitrate (1:1)HCID 189610702-Oxo-5-(3-pyridyl)thiazolidine-4-carboxylic acid

Product 1

HCID 18961040N-(2-Nitrooxyethyl)-2-oxo-5-(3-pyridyl)thiazolidine-4-carboxamide

Procedure

A procedure similar to that described in Example 1 was repeated, but using 300 mg of N-(2-nitrooxyethyl)-amine nitrate and 330 mg of 2-oxo-5-(3-pyridyl)thiazolidine-4-carboxylic acid, to obtain 140 mg of the title compound as colorless crystals, melting at 139°-140° C. (after recrystallization from ethanol).

Workup

  1. customto obtain
  2. custom140 mg of the title compound as colorless crystals, melting at 139°-140° C. (after recrystallization from ethanol)

Sources & evidence

ORD record
ord-43b3b62cb9bd49158f0c26f192007f3b
Source dataset
uspto-grants-1994_03
Patent number
US05298516

Reaction notes

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