HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-Hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate | HCID 53652710 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoic acid | HCID 53752372 | — |
Reaction Steps
A solution of methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate (139 mg, 430 μmol), ethanol (1 mL) and sodium hydroxide (1N, 440 μL, 440 μmol) was stirred at room temperature for two hours. The crude mixture was purified by flash chromatography on a 20 mm ID silica gel column. Elution of the column with choloform:acetic acid (40:1/v=v) gave title compound as a colorless gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298655 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-38b575bca1d94ac9b544ec23065db09a |
| Source note | uspto-grants-1994_03 |