HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Octadecyloxy)-5-(3-phenoxypropoxy)benzoic acid phenylmethyl ester → 3-(Octadecyloxy)-5-(3-phenoxypropoxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Octadecyloxy)-5-(3-phenoxypropoxy)benzoic acid phenylmethyl ester | HCID 15232833 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-(Octadecyloxy)-5-(3-phenoxypropoxy)benzoic acid | HCID 15232834 | 95% |
Reaction Steps
A mixture of 14.6 g of 3-(octadecyloxy)-5-(3-phenoxypropoxy) benzoic acid phenylmethyl ester and 3 g of 10% palladium on carbon in 200 ml THF and 20 ml ethyl acetate was shaken in a hydrogen atmosphere at room temperature for 2 hours. The catalyst was removed by filtration and the filtrate was concentrated to a solid which was recrystallized from ether-hexane to give 11.8 g (95% yield, mp 79°-81°) of 3-(octadecyloxy) -5-(3-phenoxypropoxy)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298652 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-96f09601eed14b409cc04c9564e81934 |
| Source note | uspto-grants-1994_03 |