Sodium Hydroxide → HCID 19091763, compound

HRID 488262Notes

Reaction equation

HRID 488262 reaction equation
[OH-].[Na+].C([O:5][C:6](=[O:55])[CH2:7][N:8]([CH2:49][C:50]([O:52]CC)=[O:51])[C:9](=[O:48])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:13]=[C:12]([O:35][CH2:36][CH2:37][CH2:38][O:39][C:40]2[CH:45]=[CH:44][C:43]([O:46][CH3:47])=[CH:42][CH:41]=2)[CH:11]=1)C>>[C:6]([CH2:7][N:8]([C:9](=[O:48])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:13]=[C:12]([O:35][CH2:36][CH2:37][CH2:38][O:39][C:40]2[CH:45]=[CH:44][C:43]([O:46][CH3:47])=[CH:42][CH:41]=2)[CH:11]=1)[CH2:49][C:50]([OH:52])=[O:51])([OH:55])=[O:5]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 19091759N-(2-ethoxy-2-oxoethyl)-N-[3-[3-(4-methoxyphenoxy)propoxy]-5-(octadecyloxy)benzoyl]glycine ethyl ester

Product 1

HCID 19091763HCID 19091763, compound

Procedure

Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[3-[3-(4-methoxyphenoxy)propoxy]-5-(octadecyloxy)benzoyl]glycine ethyl ester as in Example 11 gave N-(carboxymethyl)-N-[3-[3-(4-methoxyphenoxy)propoxy]-5-(octadecyloxy)benzoyl]glycine which gave nmr and mass spectra consistent with the structure.

Sources & evidence

ORD record
ord-b915613ebaff476b9192f59678c8fbd9
Source dataset
uspto-grants-1994_03
Patent number
US05298652

Reaction notes

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