Sodium Hydroxide → HCID 53804530, compound

HRID 488264Notes

Reaction equation

[OH-].[Na+].C([O:5][C:6](=[O:46])[CH2:7][N:8]([CH2:40][C:41]([O:43]CC)=[O:42])[C:9](=[O:39])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:13]=[C:12]([C:35]([O:37]C)=[O:36])[CH:11]=1)C>>[C:41]([CH2:40][N:8]([C:9](=[O:39])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:13]=[C:12]([C:35]([OH:37])=[O:36])[CH:11]=1)[CH2:7][C:6]([OH:46])=[O:5])([OH:43])=[O:42]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 19091805HCID 19091805, compound

Product 1

HCID 53804530HCID 53804530, compound

Procedure

Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[3-methoxycarbonyl-5-(octadecyloxy)benzoyl]glycine ethyl ester as in Example 11 gave N-(carboxymethyl)-N-[3-carboxy-5-(octadecyloxy) benzoyl]glycine, mp 108°-112°. The nmr and mass spectra were compatible with the structure.

Sources & evidence

ORD record: ord-46ed5aae47d6411ea54d9994d8d01e2a
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05298652

Reaction notes

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