Sodium Hydroxide → N-(carboxymethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine
Reaction equation
[OH-].[Na+].C[O:4][C:5](=[O:48])[CH2:6][N:7]([CH2:43][C:44]([O:46]C)=[O:45])[C:8](=[O:42])[C:9]1[CH:14]=[C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:12]=[C:11]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH:10]=1>>[C:5]([CH2:6][N:7]([C:8](=[O:42])[C:9]1[CH:14]=[C:13]([O:15][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:12]=[C:11]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH:10]=1)[CH2:43][C:44]([OH:46])=[O:45])([OH:48])=[O:4]Participants
3
Procedure
Sodium hydroxide hydrolysis of N-(2-methoxy-2-oxoethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine methyl ester gave N-(carboxymethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine, mp 93°-95°.
Sources & evidence
- ORD record
- ord-28d432116109447687a2fad7d10899ca
- Source dataset
- uspto-grants-1994_03
- Patent number
- US05298652
Reaction notes
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