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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488271Generated: October 28, 2026

N-(carboxymethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine → N-(carboxymethyl)-N-[3-hydroxy-5-(octadecyloxy)benzoyl]glycine

https://huagongshe.com/reaction/488271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(carboxymethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycineHCID 19091809—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductN-(carboxymethyl)-N-[3-hydroxy-5-(octadecyloxy)benzoyl]glycineHCID 19091766—

Reaction Steps

A mixture of 0.30 g of N-(carboxymethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine and 0.1 g of 10% palladium on carbon in 25 ml of THF was stirred in a hydrogen atmosphere for 2 hours. The usual workup followed by recrystallization from ether-hexane gave N-(carboxymethyl)-N-[3-hydroxy-5-(octadecyloxy)benzoyl]glycine, mp 160°-164°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05298652
Source datasetuspto-grants-1994_03
ORD IDord-d90564ba45fc48a6a5ba4a46872d34a3
Source noteuspto-grants-1994_03